super hox cluster – I Fly Bio

NK genes

By Sambrani | May 7, 2021

Comparison of whole genome sequences from different representatives animals revealed that HOX, PARA HOX and NK were originally close to each other in the genome, forming a big mega cluster / super Hox cluster and later would have followed different evolutionary paths in each lineage. The expression pattern of these three gene clusters are also… Read More »

Antennapedia mega cluster and Super Hox cluster

By Sambrani | May 7, 2021

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Hox genes are expressed along the anterior-posterior (A/P) body axis in majority of animals , creating a unique A/P code which plays a pivotal role in segment specific morphogenesis. These homeodomain containing transcription factors are evolutionary conserved at the level of structure ,function and organization. This is best exemplified by their presence in clusters in… Read More »