Tag Archives: Neurodegenerative

Abnormal accumulation of proteins in neurodegenerative disorders

By | June 29, 2021

Alzheimer’s disease: A microtubule-binding protein called tau abnormally aggregates in the nerve cells, glia, and extracellular space in Alzheimer’s disease. These accumulated tau molecules are highly phosphorylated and are arranged into long, thin polymers that wind around one another to form helical filaments. The helical filaments form bundles in dendrites, axon, and cell bodies that… Read More »