Tag Archives: loss of function

Flp Frt system another gift from Yeast to Fly

By | April 17, 2021

“Yeast” Saccharomyces cerevisiae has contributed immensely in making Drosophila melanogaster a successful model system.The over expression system of UAS GAL4, which is borrowed from Yeast turned out to be real boon for fly geneticists.Another significant contribution came in the form of FLP FRT technique. The system uses the 2um plasmid of the yeast Saccharomyces cerevisiae.This… Read More »

P-Element mutagenesis in Drosophila

By | April 17, 2021

There has been a long history of innovation and development of tools for gene discovery and genetic analysis in Drosophila melanogaster. This includes methods to induce mutations and to screen for those mutations that disrupt specific processes, methods to map mutations genetically and physically, and methods to clone and characterize genes at the molecular level.Modern… Read More »