Tag Archives: Drosophila

Drosophila Research Technician position

By | May 28, 2021

The Johnston Lab at Columbia University Medical Center in New York has an opening for a Research Technician. The candidate will be the primary technical support staff person for the lab, and have the opportunity for full participation in research.  Duties will include Drosophila genetics and dissection of larval, pupal and adult tissues; molecular biology… Read More »

Nomenclature of Hox genes

By | May 6, 2021

Lots of confusion prevailed in nomenclature Hox genes , even the name Hox was confusing. A hox gene originally referred to any gene coding for a protein with Homeodomain. In the beginning very few genes where known which could be clearly identified with homeotic mutants of Drosophila. Later huge number of genes with Homeodomain were… Read More »

Drosophila Fushi Tarazu : A segmentation gene with ancient Hox function

By | May 6, 2021

Evolution is not always about inventing new proteins but using the same old proteins in different ways to attain a new function and thereby modifying the body plan, leading to the development of new species. Drosophila fushi tarazu serves as a great example for evolution in action and this was demonstrated by Ulrike Lohr lab… Read More »

Edward B. Lewis: A Pioneer in real sense

By | May 5, 2021

Genetics is a discipline initially worked out by Gregor Mendel (Austrian monk) using common pea plants in his garden. Since then many great minds used genetics to understand important problems of biology, including the study of evolution and how plants and animals develop. The power of genetics and its importance to mankind was first time… Read More »

Best Drosophila books for the beginners

By | May 3, 2021

Drosophila  happens to be a favorite model organism for many ever since Morgan started using it for genetic studies 100 years ago. This tiny arthropod has solved many biological puzzles ,thanks to various researchers working on fruit fly all over the world.Initially the word genetics might be scary for beginners as it involves complicated crosses… Read More »

Heart development in Drosophila

By | May 2, 2021

Introduction:Looks might be really deceiving and this statement holds true in case of heart formation in organisms. Even though Drosophila heart which looks very different from its vertebrates counter parts, but The molecular pathways controlling heart formation and differentiation are evolutionarily conserved. The similar rules in forming heart in flies and higher vertebrates and availability… Read More »

How do Hox proteins function

By | May 2, 2021

The enormous diversity in body plan among the various organisms in animal kingdom is partly contributed by the Hox genes.Hox proteins regulate gene expression in different ways and thereby generating different body plans.Most of the organisms on earth have one or more clusters of Hox genes.These Hox genes pattern different segment and thus gives a… Read More »

Hox Genes or Homeotic genes in Development

By | May 1, 2021

Homeotic genes/ Hox genes encode transcription factors, which play an important role in giving a unique identity to each segment and thereby setting up morphogenesis along the anterior posterior axis.They are recognizable by the presence of a 60 amino acid long DNA binding region called the homeodomain, but all homeo domain containing proteins are not… Read More »

Discovery of Homeodomain

By | May 1, 2021

If we stroll back in the memory lane , History was created in 1983 with the discovery of Homeodomain independently by two groups headed by Walter Gehring and his colleagues at the University of Basel, Switzerland, and Matthew Scott and Amy Weiner, who were then working with Thomas Kaufman at Indiana University in Bloomington. Homeodomain… Read More »