Tag Archives: andrew fire

RNA interference / RNAi : Tool for loss of function in Drosophila

By | April 17, 2021

RNAi was first described and named so by molecular biologists Andrew Fire of the Carnegie Institute of Washington and Craig Mello of the University of Massachusetts, along with their colleagues, in a landmark 19 February 1998 Nature paper.In RNAi ,double stranded RNA(ds RNA) is cleaved invivo by Dicer Ribonuclease into 21-23 nucleotide small interfering RNA(si… Read More »